Culture PCR Species Risk Factors Site Empiric Therapy Targeted Therapy Surgery IFD Final Response Patient alive Year of Infection
Trichosporon asahii Cancer Other (Acute Leukemia), Corticosteroids, Immunosuppression, Chemotherapy, Neutropenia Blood, Disseminated Liposomal amphotericin B Voriconazole Complete Response Yes 2017
Trichosporon asahii Cancer Other (Ewing's sarcoma), Hematopoietic stemm cell transplantation (HSCT) Blood, Kidneys, Lungs, Disseminated Amphotericin B lipid complex, Fluconazole, Caspofungin Deterioration or failure No 2015
Trichosporon asahii Alcoholism, Chronic liver disease, ICU CNS Fluconazole Complete Response Yes 2012
Trichosporon spp. Cancer (AML), Chemotherapy, ICU, Neutropenia Blood Amphotericin B lipid complex, Voriconazole Deterioration or failure No 2011
Trichosporon spp. Cancer (AML), Chemotherapy, ICU, Neutropenia Blood, Lungs, Skin Micafungin Micafungin, Voriconazole, Amphotericin B lipid complex Complete Response Yes 2011
Trichosporon spp. Cancer (AML), Chemotherapy, ICU, Neutropenia Blood, Deep soft tissues, Kidneys, Liver, Lungs Micafungin Amphotericin B lipid complex Deterioration or failure No 2011
Trichosporon mycotoxinovorans Chronic pulmonary disease, Diabetes mellitus, ICU, Solid organ transplantation Blood, CNS, Gastrointestinal tract, Kidneys, Liver, Lungs, Other: Heart Liposomal amphotericin B, Caspofungin, Voriconazole Liposomal amphotericin B, Voriconazole, Caspofungin Deterioration or failure No 2011
Trichosporon spp. ICU, Major surgery, Other: Premature birth Blood Amphotericin B deoxycholate Amphotericin B deoxycholate, Fluconazole Deterioration or failure No 2008
Trichosporon asahii Alcoholism, Chronic liver disease, Chronic renal disease, ICU, Solid organ transplantation Blood Fluconazole, Caspofungin, Amphotericin B lipid complex Amphotericin B lipid complex, Caspofungin, Itraconazole Partial Response No 2003
Culture available Trichosporon asahii ICU, Major surgery Blood, Other: Wound infection Fluconazole, Caspofungin Complete Response Yes 2006
Culture available Trichosporon asahii Cancer (ALL), Chemotherapy, Hematopoietic stem cell transplantation (HSCT), ICU, Neutropenia Blood Amphotericin B deoxycholate, Voriconazole Deterioration or failure No 2009
Culture available Trichosporon asahii Alcoholism, Chronic liver disease Blood Deterioration or failure No 2014
Trichosporon spp. Cancer (AML), Chemotherapy, Neutropenia Blood, Lungs Micafungin Unknown No 2003
Trichosporon asahii Cancer (ALL), Hematopoietic stem cell transplantation (HSCT) Blood, CNS Caspofungin Voriconazole Deterioration or failure No 2013
Trichosporon asahii Cancer (AML), Chemotherapy, Neutropenia Blood, Lungs Posaconazole Complete Response Yes 2011
Trichosporon asahii Cancer (Lymphoma), Chemotherapy, Neutropenia Blood, Bones, Deep soft tissues, Eyes, Liver, Spleen, (First only blood, later dissemination to organs) Caspofungin Caspofungin, Voriconazole Partial Response Yes 2010
Trichosporon spp. Cancer (AML), Chemotherapy, Neutropenia Lungs Caspofungin, Voriconazole, Fluconazole Liposomal amphotericin B, Voriconazole Complete Response Yes 2011
Trichosporon asahii Chemotherapy Blood Caspofungin Voriconazole Deterioration or failure No 2011
Trichosporon asahii Cancer (ALL), Chemotherapy, Hematopoietic stem cell transplantation (HSCT), Neutropenia Blood, CNS, Kidneys, Lungs Deterioration or failure No 2011
Culture available Trichosporon asahii No risk factor identified Paranasal sinus(es) Voriconazole Functional endoscopic sinus surgery Complete Response Yes 2011
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Principle Investigator:
Prof. Oliver A. Cornely, MD, FACP, FIDSA, FAAM, FECMM, Cologne, Germany
Project Manager:
Danila Seidel, PhD, Cologne, Germany
Coordinating physician:
Maria J. G. T. Vehreschild, MD, Cologne, Germany
Epidemiology & Statistics:
J. Janne Vehreschild, MD, FECMM, Cologne, Germany