Culture PCR Species Risk Factors Site Empiric Therapy Targeted Therapy Surgery IFD Final Response Patient alive Last Observed
Culture available Trichosporon asahii Chemotherapy, ICU, Neutropenia Blood, Lungs Liposomal amphotericin B Liposomal amphotericin B, Voriconazole Deterioration or failure No 2008
Culture available Trichosporon asahii Chronic renal disease, ICU, SOT Blood Fluconazole Complete Response No 2009
Trichosporon asahii Chemotherapy, HSCT, ICU, Neutropenia Blood Amphotericin B deoxycholate, Voriconazole Deterioration or failure No 2009
Culture available Trichosporon faecale ICU, Other: A pregnant patient had right pyelonephritis, left megaureter, right minimal pleural effusion, Intrauterine feotal death. Kidneys Voriconazole Complete Response Yes 2009
Culture available Trichosporon asahii ICU, Major surgery Blood, Wound infection Fluconazole, Caspofungin Complete Response Yes 2008
Culture available Trichosporon asahii Chemotherapy, ICU, Neutropenia Blood, knee articulation Fluconazole Deterioration or failure No 2006
Culture available Trichosporon asahii HSCT, ICU Blood Fluconazole Complete Response Yes 2008
Trichosporon asahii Alcoholism, Chronic liver disease, Chronic renal disease, ICU, SOT Blood Fluconazole, Caspofungin, Amphotericin B lipid complex Amphotericin B lipid complex, Caspofungin, Itraconazole Partial Response No 2004
Trichosporon sp. ICU, Major surgery, Premature birth, Other: extremely low-birth-weight infant Blood Amphotericin B deoxycholate Amphotericin B deoxycholate, Fluconazole Deterioration or failure No 2008
Trichosporon asahii Chemotherapy, ICU, Neutropenia Blood, Kidneys, Liver, Spleen Liposomal amphotericin B Voriconazole Deterioration or failure No 2005
Culture available Trichosporon asahii Chemotherapy, ICU, Neutropenia Blood Posaconazole solution, Caspofungin Caspofungin Cholecystektomie Deterioration or failure No 2009
Trichosporon sp. Chemotherapy, ICU, Neutropenia Blood, Deep soft tissues, Lungs Amphotericin B deoxycholate Amphotericin B deoxycholate, Caspofungin, Voriconazole Deterioration or failure No 2011
Culture available Trichosporon asahii ICU, No risk factor identified Paranasal sinus(es) Voriconazole functional endoscopic sinus surgery Complete Response Yes 2011
Trichosporon asahii Chemotherapy, HSCT, ICU, Neutropenia Blood, CNS, Kidneys, Lungs Deterioration or failure No 2011
Trichosporon asahii Chemotherapy, ICU Blood Caspofungin Voriconazole Deterioration or failure No 2011
Trichosporon sp. Chemotherapy, ICU, Neutropenia Lungs Caspofungin, Voriconazole, Fluconazole Liposomal amphotericin B, Voriconazole Complete Response Yes 2011
Trichosporon asahii Chemotherapy, ICU, Neutropenia Blood, Bones, Deep soft tissues, Eyes, Liver, Spleen, First only blood, later dissemination to organs Caspofungin Caspofungin, Voriconazole Partial Response Yes 2012
Trichosporon mycotoxinovorans Chronic pulmonary disease, Diabetes mellitus, ICU, SOT Blood, CNS, Gastrointestinal tract, Kidneys, Liver, Lungs, Heart Liposomal amphotericin B, Caspofungin, Voriconazole Liposomal amphotericin B, Voriconazole, Caspofungin Deterioration or failure No 2011
Trichosporon asahii Chemotherapy, ICU, Neutropenia, nonhodgkin lymphoma Blood, Lungs Posaconazole solution Complete Response Yes 2012
Trichosporon sp. Chemotherapy, ICU, Neutropenia Blood, Deep soft tissues, Kidneys, Liver, Lungs Micafungin Amphotericin B lipid complex Deterioration or failure No 2011
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Principle Investigator:
Prof. Oliver A. Cornely, MD, FACP, FIDSA, FAAM, FECMM, Cologne, Germany
Project Manager:
Danila Seidel, PhD, Cologne, Germany
Coordinating physician:
Maria J. G. T. Vehreschild, MD, Cologne, Germany
Epidemiology & Statistics:
J. Janne Vehreschild, MD, FECMM, Cologne, Germany