Culture PCR Species Risk Factors Site Empiric Therapy Targeted Therapy Surgery IFD Final Response Patient alive Year of Infection
Bisifusarium dimerum ICU, Trauma Eyes Fluconazole, Subconjunctival liposomal amphotericin B Subconjunctival liposomal amphotercin B, Liposomal amphotericin B - Complete Response Yes 2010
Bisifusarium dimerum Chronic renal disease, ICU, Major surgery, CLL Lungs Fluconazole, Voriconazole - - Complete Response Yes 2008
Culture available Bisifusarium dimerum Diabetes mellitus, ICU Eyes - Natamycin, Fluconazole Therapeutic penetrating keratoplasty Stable Disease Yes 2009
Culture available Bisifusarium dimerum Alcoholism, Diabetes mellitus, ICU Eyes - Natamycin - Partial Response Yes 2007
Fusarium fujikuroi HSCT, ICU Blood, Skin, Knee Amphotericin B deoxycholate, Liposomal amphotericin B, Voriconazole Liposomal amphotericin B, Voriconazole - Complete Response Yes 2006
Fusarium fujikuroi Chemotherapy, HSCT, ICU, Neutropenia Lungs Caspofungin, Liposomal amphotericin B - - Complete Response No 2010
Culture available Fusarium fujikuroi Chemotherapy, ICU, Neutropenia Blood, Lungs, Skin Caspofungin, Posaconazole Liposomal amphotericin B, Voriconazole - Deterioration or failure No 2009
Culture available Fusarium fujikuroi species complex Chronic cardiovascular disease, HSCT-Allogeneic Lung - - - Complete Response No 2017
Culture available Fusarium incarnatum Diabetes mellitus, ICU Deep soft tissues, Skin, Synovialis - Liposomal amphotericin B - Partial Response Yes 2009
Culture available Fusarium incarnatum ICU, SOT Bones, Deep soft tissues - Amphotericin B deoxycholate, Voriconazole Amputation Partial Response Yes 2007
Fusarium moniliforme Chemotherapy, ICU, Neutropenia Skin Caspofungin Liposomal amphotericin B, Voriconazole - Complete Response Yes 2013
Fusarium moniliforme HSCT, ICU, Shwachman-Bodian-Diamond Syndrome Blood, Skin, Probably joints of left hand - Liposomal amphotericin B, Voriconazole Debridement of the skin lesions of the soles Complete Response Yes 2015
Culture available Fusarium musae Chemotherapy, HSCT, ICU, Neutropenia Blood, Skin Posaconazole Caspofungin, Voriconazole - Complete Response No 2015
Culture available Fusarium oxysporum Chemotherapy, ICU, Neutropenia Blood Caspofungin, Voriconazole Isavuconazole - Deterioration or failure No 2012
Culture available Fusarium oxysporum Chronic pulmonary disease, Diabetes mellitus, ICU Lungs - Voriconazole - Partial Response Yes 2009
Culture available Fusarium oxysporum Chronic renal disease, Diabetes mellitus, ICU, Coronary heart disease, Malignant synovioma Blood - Voriconazole - Partial Response Yes 2015
Fusarium oxysporum Chemotherapy, HSCT, ICU, Neutropenia Blood - Liposomal amphotericin B, Voriconazole - Complete Response Yes 2010
Fusarium oxysporum Chemotherapy, ICU, Major surgery, Neutropenia, CVC, Hypogammaglobulinemia Lungs, Paranasal sinus(es) - Fluconazole, Voriconazole, Amphotericin B lipid complex - Deterioration or failure No 2012
Culture available Fusarium petroliphilum ICU Eyes - Liposomal amphotericin B, Amphotericin B deoxycholate, Voriconazole Cornea transplantation twice Partial Response Yes 2014
Culture available Fusarium proliferatum Diabetes mellitus, HSCT, ICU, Prolonged neutropenia (3 month) Blood, Lungs, Paranasal sinus(es), Skin Amphotericin B lipid complex, Voriconazole Posaconazole, Terbinafine Bilateral nasal endoscopy with endoscopic resection of invasive fungal rhinosinusitis. Deterioration or failure No 2008
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Principle Investigator:
Prof. Oliver A. Cornely, MD, FACP, FIDSA, FAAM, FECMM, Cologne, Germany
Project Manager:
Danila Seidel, PhD, Cologne, Germany
Coordinating physician:
Maria J. G. T. Vehreschild, MD, Cologne, Germany
Epidemiology & Statistics:
J. Janne Vehreschild, MD, FECMM, Cologne, Germany